Have you ever been through the streets of their town, pubs and bars that are adjacent to the party late Saturday night? If you answer "Yes", then you have met some people from stumbling, unable to speak properly, and said that the world revolves around you! I think to ignore their demands, which is "a little drunk." So what will happen to these people when they eat or drink alcohol? It may be a little more dangerous and complicated than we think ... canAlcohol
Although "alcohol" in the nomenclature generally refers to the entire family of organic compounds such as methanol, ethanol, isopropanol, we find that ethanol "when it comes to alcohol, contained in the rules for these chemicals.
Alcohol, ethanol (C2H5OH) is in particular an organic compound consisting of molecules composed of carbon, hydrogen and oxygen. It is a volatile liquid with a characteristic odor, a high affinity for water. In fact, its high solubility in water, one of the most powerful human central nervous system depressant. It is a potent sedative hypnotic with a number of side effects. The quantity is affected to the extent that the central nervous system depends on the concentration of alcohol in the blood, usually alcohol concentration (BAC) refers.
Effects on the initial phase
When ingested, the effects of alcohol on the human body over time. In the initial phase, the person feels more relaxed and happy, the next trip over the animation movements and speech. They are more confident, without inhibitions. This occurs because of increased metabolism in the nigrostriatal pathway in the brain that are associated with body movements. Then increased alpha brain waves homosexual person, relax, alcohol stimulation of the cortex, the hippocampus in the brain get rid of inhibitions. This step is often described as euphoria, where alcohol is from 0.03 to 0.12% above.
Absorption and Distribution Mechanism
When consumed, alcohol irritates the lining and then into the esophagus caused a numbing effect. So he goes to the stomach, where only 20% of the total amount absorbed by it. The remaining 80% is absorbed by the small intestine where it is widespread in the human body. Alcohol crosses the blood and enter the vicinity of the cells of almost all organs. As already mentioned, because of its high affinity for water penetration in almost all cell membranes, resulting in the absorption of all institutions.
Metabolism and its effects
Alcohol dehydrogenase, an enzyme secreted by the liver converts alcohol to acetaldehyde. This is then converted to acetaldehyde to acetic acid and acetate, followed by acetaldehyde dehydrogenase. Acetate is a combination of fat that is stored locally. Due to chronic alcohol consumption, and continues, increased fatty acid leads to the formation of plaques in the capillaries of the liver. This leads to cirrhosis. Since the liver plays a crucial role in filtering mechanism of dysfunction of the body, liver, often leading to jaundice (hepatitis). Since alcohol increases the secretion of ADH is more urine, leading to dehydration.
Carcinogenic effects
Alcohol is classified as a Group 1 carcinogen by the WHO. Although previous studies have failed to establish a direct correlation between alcohol and its effect on cancer, there is strong evidence that alcohol increases the effects of other cancer-causing chemicals snuff. Acetaldehyde, a byproduct of alcohol metabolism, so when concentrated in large quantities can damage DNA in cells. Its reaction with polyamines can be found mutagenic DNA. Excessive intake of ethanol is also the mouth, larynx, pharynx, esophagus more prone to cancer.
Effects on the human body
There are several effects of alcohol on the human body is subject to their concentrations in the blood. They are generally classified as follows-
- When BAC count ranging from 0.09 to 0.23% is present, the condition is known as stupidity. In this state, people become sleepy, their movements lose coordination, start to lose their balance in the body. It is also characterized by blurred vision.
- where the BAC count ranging from 0.17 to 0.28% is present, the condition is known as the confusion. This is compounded by the emotional state where people are trying to be sentimental, is the hallmark of aggressive. Not sure what they do. Dizziness continues. Nausea is a common symptom of this phase.
- When BAC count from 0.25 to 0.39% at present, the condition is known as stupor. At this stage, the movements of the body are affected and patients lose consciousness again and again. They have a high risk of coma or death.
- When the blood alcohol count of 0.35 to 0.50% is present, the condition is known as a coma. It is characterized by unconsciousness when body reflexes are low, breathing decreases, which reduces the heart rate.
- When BAC crosses the threshold of 0.5%, resulting in an error in the central nervous system (CNS) led eventually to death.
Alcoholism is a public health problem. While alcohol is the development of a number of diseases, but also develop withdrawal symptoms such as delirium tremens, a high percentage of mortality (35%) when not treated. During pregnancy, alcohol can cause fetal alcohol.